产品货号：
Z30429
中文名称：
ZEB2抗体
英文名称：
Anti-ZEB2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ZEB2 Antibody |
| 指标别名 | KIAA0569;SIP 1;SIP1;Smad interacting protein 1;SMADIP1;ZEB2;ZFHX1B;ZFX1B |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | ZEB2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human ZEB2(948-962aa DMQQRRKYQRKQGFQ),identical to the related rat and mouse sequences. |
| 实际分子量 | 136～200KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ZEB2(Zinc finger E-box-binding homeobox2),also known as SIP1or ZINC FINGER HOMEOBOX 1B(ZFHX1B),is a protein that in humans is encoded by the ZEB2 gene.The ZEB2 gene is a member of the ZEB1/Drosophila Zfh1 family of 2-handed zinc finger/homeodomain proteins and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs,the transducers of TGF-beta signaling,and interacts with the nucleosome remodeling and histone deacetylation(NURD) complex.By radiation hybrid analysis,Nagase et al.(1998) mapped the ZEB2 gene to chromosome 2.Wakamatsu et al.(2001) mapped the ZEB2 gene to chromosome 2q22.Vandewalle et al.(2005) showed that expression of mouse Sip1 in human epithelial cells caused a morphologic change from an epithelial to a mesenchymal phenotype.Expression of SNAI1 in epithelial cells triggers an epithelial-mesenchyme transition.Beltran et al.(2008) showed that synthesis of ZEB2 was upregulated following SNAI1 expression in human cell lines. |
| Uniprot ID | O60315 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | zinc finger E-box binding homeobox 2 |
| 蛋白名全称 | Zinc finger E-box-binding homeobox 2 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：ZEB2抗体，ZEB2多抗，Anti-ZEB2 Antibody